Cell

A cell in the Gungeon Proper with Tonic trapped inside.

Cells are special rooms that can be encountered in Enter the Gungeon, placed throughout the Gungeon once certain requirements have been met. They serve as an important part of Enter the Gungeons meta-progression, as they each contain an incarcerated NPC who can be freed to appear on future runs, or in the Breach.

Cells each contain a special golden lock-a-doora (lock) which cannot be opened with regular Keys. Instead, they require a Cell Key to gain access. If a cell has generated in the current chamber, a random enemy on the floor is assigned to drop a Cell Key. The enemy chosen is more likely to be a powerful foe, such as a Gun Nut, and can even be the chamber boss.

List of Cells

Different cells have different requirements dictating when they are allowed to appear. This includes what chambers they can appear in, and what progression milestones must be met. All progression milestones are evaluated per save file.

Cells listed as appearing in Most chambers can appear in the Keep of the Lead Lord, Oubliette, Gungeon Proper, Abbey of the True Gun, Black Powder Mine, and Hollow.

Locked NPC	Chambers	Other Criteria and Notes
Cadence & Ox (Early)	Keep of the Lead Lord	The player must have entered the Gungeon at least 3 times.
Cadence & Ox	Gungeon Proper	Has no special criteria, however this cell is extremely prioritised over other NPC cells that might appear in this Chamber.
The Lost Adventurer	Most	The player must have entered the Gungeon Proper at least 5 times.
Professor Goopton	Most	The player must have entered the Gungeon Proper at least 6 times.
Doug	Most	The player must have entered the Gungeon Proper at least 6 times.
Old Red	Most	The player must have held at least 4 Blanks at once at some point. It does not have to be on the same run in which the Cell is encountered.
Cursula	Most	The player must have had a Curse level higher than 0 at any point on the current save file. It does not have to be on the same run in which the Cell is encountered.
Flynt	Most	The player must have held at least 4 Keys at once at some point. It does not have to be on the same run in which the Cell is encountered.
Frifle and the Grey Mauser	Most	The player must have entered the Gungeon Proper at least 5 times.
Ledge Goblin (First Encounter)	Most	The player must have entered the Gungeon Proper at least 9 times.
Ledge Goblin (Second Encounter)	Gungeon Proper	The player must have kicked the Ledge Goblins helmet into the pit in the Breach.
Ledge Goblin (Third Encounter)	Black Powder Mine	The player must have kicked the Ledge Goblins helmet into the pit in the Breach again, after rescuing her from the second cell.
Ledge Goblin (Fourth Encounter)	Hollow	The player must have kicked the Ledge Goblins helmet into the pit in the Breach a third time, after rescuing her from the third cell.
Gunsling King and Manservantes	Most	The player must have entered the Gungeon Proper at least 5 times.
Synergrace	Most	The Lost Adventurer and the Gunsling King must have already been rescued.
Vampire	Most	Cursula and Frifle and the Grey Mauser must have already been rescued.
Sorceress	All except R&G Dept., Resourceful Rat's Lair, and Bullet Hell	The player must have entered the Gungeon Proper at least 25 times, and have killed the High Dragun.
Daisuke	All except R&G Dept., Resourceful Rat's Lair, and Bullet Hell	The player must have already rescued the Sorceress OR used the Chance Shrine at least twice and killed the High Dragun.
Tonic	Most	The Sorceress must have already been rescued.
Bowler	Most	The Sorceress must have already been rescued.

Cut Content

• In pre-release versions of Enter the Gungeon, cell rooms did not have broad side areas. These side wings were likely added to permit entry to Cell rooms from the north. Additionally in these versions, the special golden lock securing the cell door was much smaller and did not appear to be alive.

• 

  The appearance of a Cell in pre-release versions of ETG.

Notes

• Cells appear on the map with a unique icon,
• Since Cells only appear to facilitate NPC unlocks, once all NPCs have been unlocked, Cells will no longer appear.
• Cells can never appear in the R&G Dept., Resourceful Rat's Lair, or Bullet Hell.